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Advanced Screening
LABORATORY SERVICE
Overview
LAMPIRE’s Advanced Monoclonal Screening platform delivers comprehensive antibody characterization to support confident lead selection and downstream development. By combining advanced instrumentation with customizable assay design, our platform generates actionable data across binding, kinetics, epitope differentiation, and functional performance.
This multi‑dimensional approach allows antibodies to be evaluated beyond simple binding, providing deeper insight into biological relevance and reducing risk as programs progress. Screening strategies are designed to align with discovery goals, enabling focused evaluation of promising candidates without reliance on large, unfocused libraries.
Complimentary Antigen Design and Protocol Review
Take advantage of our complimentary Antigen Design and Protocol Review to optimize your custom antibody development strategy. Our scientific experts provide tailored solutions for difficult targets, antibody production, downstream testing, and specialized laboratory services, delivering the technical expertise needed to maximize project success.
Why Choose Us?
Trusted experts in advanced antibody screening
Strategic focus on effiency: evaluating selected clones without building massive libraries
Proven ability to translate screening data into downstream efficacy and functional insights
Flexible and tailored approach to meet specific program goals
Collaborative scientific support that helps clients make faster, smarter decisions
Capabilities
- Target binding analysis using on‑cell and overexpression systems
- Functional activity and internalization studies with customized assay design
- EC50 determination and comparative binder ranking
- Kinetic characterization using SPR and BLI methodologies
- Off‑rate analysis and full kinetic profiling
- Epitope binning and competition assays
- Bi‑directional matrix and epitope differentiation studies
Benefits
- Confident Lead Selection: Antibodies are evaluated across binding, kinetics, epitope engagement, and functional performance to support informed prioritization.
- Reduced Downstream Risk: Early identification of functional and non‑redundant antibodies minimizes attrition later in development.
- Focused Screening Efficiency: Strategic evaluation of selected candidates accelerates discovery without unnecessary library expansion.
- Deeper Understanding of Antibody Behavior: Multi‑parameter datasets provide insight into biological relevance beyond simple affinity measurements.
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