Rabbit Monoclonal Antibodies
Custom rabbit monoclonal antibody development services designed for research, diagnostic, and therapeutic applications. Combining the high affinity and epitope recognition of the rabbit immune system with advanced monoclonal antibody technologies, we help accelerate the discovery of high-performance antibodies for challenging targets.

MONOCLONAL ANTIBODY SERVICE

Overview

LAMPIRE’s Rabbit Monoclonal platform delivers high specificity antibodies with reduced off target effects by leveraging the natural strengths of the rabbit immune system. Rabbit antibodies consistently exhibit higher affinity and broader epitope recognition than traditional murine models, making them well suited for challenging targets and sensitive assay applications.

Using an integrated single B cell workflow, LAMPIRE supports rabbit monoclonal discovery from immunization through recombinant expression. Antigen specific B cell isolation and direct sequence recovery enable a transparent, sequence forward approach, with all validated sequences delivered to the client with full IP ownership and flexibility for downstream development.

Complimentary Antigen Design and Protocol Review

Take advantage of our complimentary Antigen Design and Protocol Review to optimize your custom antibody development strategy. Our scientific experts provide tailored solutions for difficult targets, antibody production, downstream testing, and specialized laboratory services, delivering the technical expertise needed to maximize project success.

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Unique Species
1
Animals on US Farms
6000
Vivariums
10
Custom Projects Annually
800

Why Choose Us?

High - Affinity Antibodies

Antigen-Specific B Cell Isolation

Paired VH and VK Sequences

End-To-End Workflow

US-Based, AAALAC accredited

Capabilities

  • Custom rabbit immunization campaigns tailored to antigen type and project goals
  • Support for diverse antigen formats including proteins, peptides, soluble membrane proteins, nanodiscs, and VLPs
  • Antigen specific B cell isolation from PBMCs and splenocytes
  • Next generation sequencing based recovery of paired VH and VK sequence
  • Transient CHO expression with scalable yields from microgram to gram quantities
  • Primary binding confirmation using ELISA with positive and negative controls

Benefits

  • Higher Affinity Performance: Ultralong CDR3 knob domains enable engagement of complex or recessed antigen surfaces that are often inaccessible to conventional antibody formats.
  • Effective Against Difficult Targets: The rabbit immune response is well suited for small, conserved, or low immunogenic epitopes that can be challenging for other hosts.
  • Sequence Forward Transparency: Direct recovery of paired VH and VK sequences provides full visibility and long term value through client owned IP.
  • Flexible Recombinant Options: Recovered antibodies can be expressed in multiple recombinant formats with scalable production to support screening and development.

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