Lampire’s sequence‑forward, single B cell approach enables rapid discovery of high‑quality recombinant monoclonal antibodies directly from the natural immune response. By isolating antigen‑specific B cells from immunized animals, we preserve the full diversity of the native antibody repertoire—without the bias or bottlenecks associated with hybridoma or display‑based methods.

Using precision FACS sorting of B cells bound to labeled antigen, paired antibody sequences are recovered directly from PBMCs and rapidly advanced into recombinant expression and functional screening. This integrated workflow supports conventional antibodies, single‑domain formats, and novel ultralong CDR3 binders, all screened on the Fc backbone of your choice.