Single B Cell Approach

  • FACs sorting B-cells bound to labeled antigen​​

  • Robust sampling of natural antibody repertoire​​

  • Fastest timeline to sequence and screening recombinant monoclonal antibody on "FC of choice“​

  • Recovering vHH sequences from Immunized animals is less-complicated as compared to conventional mabs since they are derived from Homo-Dimeric BCRs rather than Hetero-Dimeric BCRs as in mice, rabbits and humans. ​​

  • Large quantities of PBMCs can be collected from Llamas and Alpacas across multiple timepoints during an immunization.​